Yves-Alain Barde, Cardiff University, UK:
“The lack of suitable, i.e. sensitive and specific reagents allowing the reliable detection of BDNF after Western blotting has been a real problem in the field for decades. This has now been resolved following the development by Icosagen of a remarkably useful mouse monoclonal antibody designated 3C11. It recognises mammalian BDNF and pro-BDNF on Western blot with unprecedented high selectivity and sensitivity."Brain-derived Neurotrophic Factor in Megakaryocytes. Chacón-Fernández P, Säuberli K, Colzani M, Moreau T, Ghevaert C, Barde YA. J Biol Chem. 2016 Mar 22. pii: jbc.M116.720029.