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About us

WHO WE ARE

Integrated CRO and CDMO expertise — All under one roof

Icosagen is Estonia’s largest biotechnology company and a leading
European CRDMO — Contract Research, Development, and Manufacturing Organization.

With over 26 years of experience, we uniquely combine pre-clinical CRO and clinical CDMO capabilities under one roof, enabling us to seamlessly discover, develop and manufacture protein drug candidates from research concepts up to clinical GMP manufacturing.

 

Icosagen is a research-driven contract research provider for biopharmaceutical and biotechnology industries that deftly adapts to market forces and current trends, and is always guided by the needs of its customers.

The Group comprises four entities: parent company Icosagen AS and three subsidiaries: Icosagen Cell Factory OÜ, Icosagen Technologies Inc., and IcoPark OÜ.

This is a picture of Icosagen's GMP facility.

OUR HISTORY

Over 26 years of Innovation and Scientific Excellence

Founded in the late 1990s by a group of Estonian scientists, Icosagen began its journey under the name Quattromed. After a successful spin-off and sale of its diagnostics division in 2008, the company refocused its mission on biologics development. Today, Icosagen operates under the continued leadership of Professor Mart Ustav, whose deep expertise in virology and molecular biology has guided the development of proprietary protein expression systems and advanced manufacturing capabilities.

VIEW THE TIMELINE
This timeline represents Icosagen's history.

OUR CAPABILITIES

End-to-End CRDMO Services Under One Roof

Icosagen provides a full spectrum of services across the biologics development lifecycle. From early therapeutic antibody discovery and cell line development to upstream and downstream process optimization, analytical testing, and clinical GMP manufacturing — we deliver everything in-house. This one-site, one-team, one-project model ensures full traceability, reduced handovers, and consistent quality throughout each phase of development.

DISCOVER SERVICES
This timeline represents Icosagen's history.

OUR FACILITIES

State-of-the-Art Infrastructure for Preclinical and Clinical Manufacturing

Our integrated campus in Tartu, Estonia, houses R&D laboratories, bioprocessing suites, and a newly built GMP manufacturing facility. Equipped with cutting-edge technologies and a fully digital QA documentation system, our facility enables flexible and compliant production at scales up to 1000 L. This infrastructure allows us to meet rigorous regulatory and quality standards.

OUR TEAM

230+ Experts Driving Global Biopharma Success

Icosagen employs over 230 highly skilled scientists, engineers, and technical professionals. Our multidisciplinary team brings deep expertise in molecular biology, protein engineering, cell line development, bioprocessing, and manufacturing. Whether developing early-stage candidates or supporting clinical submissions, we work in close collaboration with our clients to ensure scientific rigor, transparency, and success at every milestone.

RECOGNITION & AWARDS

Acknowledged for Excellence in Innovation and Enterprise Success

Icosagen has been nominated for Company of the Year and Innovator of the Year at Estonia’s prestigious Annual Enterprise Awards. These recognitions reflect our contributions to advancing the biotechnology sector and our leadership in bringing innovative biologics solutions to market.

Logo of Best Estonian Companies 2023 Award
Logo of Best Estonian Companies 2023 Award
  • Icosagen AS was established in 1999. Common departments, such as general management and financing/accounting and QC/QA, business development, sales and marketing are represented by the parent company. A portfolio of off-the-shelf products, such as antibodies, proteins, ELISA kits, etc., and quality control services in the field of natural rubber allergen testing and food quality control, are also part of the activities of Icosagen AS.

 

  • Icosagen Cell Factory (ICF) is the research & development service arm of Icosagen Group, established in 2005. Since then, ICF has organically grown into a mammalian Contract Research, Development and Manufacturing Organization (CRDMO) for the biopharmaceutical, biotechnology and diagnostic industry.  Our clients turn to us for custom-tailored services from discovery, hit-to-lead finding, pre-clinical candidate selection and up to early clinical candidate development. This entails antibody and protein discovery, notably including complicated proteins, their multi-parallel recombinant production, up to stable CHO cell line development and 50L production runs. By spanning the entire discovery, pre-clinical and early clinical development path, our clients save time, funds and nerves. Lengthy and error-prone tech transfers are avoided, while molecule know-how remains in house. On top of that, these integrated, semi-parallel development capabilities enable greatly accelerated development times. We are known to be scientifically knowledgeable, technically savvy and meticulous as well as quick and responsive. Our credo is quality, rapidly and economically. In 2021, Icosagen Cell Factory worked with more than 150 protein drug or vaccine developing companies globally, producing more than 1500 different proteins.

 

  • Icosagen Technologies Inc. was established in 2015, to give US customers access to Icosagen’s technologies and services.

 

  • IcoPark OÜ was established in 2013, to develop the infrastructure of the Icosagen Group.
For our customers, we provide opportunities and contributions to make their activities simpler, more efficient and less risky.

Internally, we continuously develop and improve our products, technologies and services to provide additional innovation and benefit to our customers. Our company has over 140 skilled and committed professional team members. The management system complies with the requirements of the ISO 9001:2015 standard.

We are a leading biotechnology group in Estonia having provided custom-tailored services as well as catalogue products for global customers in academia, pharma, biotech and industry for several years.