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Our therapeutic focus is on:
• multi pass transmembrane proteins
• immuno-oncology
• Infectious disease
• neuropathic pain, oncology.
• Antibody discovery
• Hybridoma sequencing
• Humanization
• Transient production
• Membrane protein expression
• ADCC Enhancement
• Cell line development
• Cell based assays
• Protein analytics
• GMP manufacturing
Our diagnostic categories:
• Cardiovascular markers
• Infectious disease
• Inflammation
• NeurobiologyÂ
• Secondary antibodies
• Latex allergensÂ
Icosagen helps its customers to focus on the pre-clinical research of therapeutic antibodies and other biologics by supplying high quality protein and antibody candidates in a timely manner.
TARGET IDENTIFIED
retrieve the
antibody
sequence
(hybri-rescue
p. 9)
existing hybridoma
protein sequence
production of a functional antigen
Antibody discovery
protein production
optimization and engineering
cell line development
functional testing and thorough quality control
molecular characterization
high quality proteins
REMEMBER: ANTIGEN MATTERS! Even the smallest difference between an antigen and the natural target protein will affect the antibody specificity and biological function.
Chicken
Fastest immunization
High affinity
DNA immunization
The best for conserved targets
Rabbit
Fast immunization
Highest affinity
Great diversity
The best for small molecules
Mouse
Slow immunization
Normal affinity
Industry standard
© 2023 Icosagen
