Frequently asked questions

Why it is not enough to measure the total protein level? 

Only some of the proteins are allergenic; total protein content does not yield reliable information about the allergenicity of a product.

Why it is not enough to measure only one allergen? 

Patients can be sensitised to one or more allergens; different gloves and other NRL products can contain different allergens.

Are all proteins and antigens from the rubber tree equally allergenic? 

No. During the rubber manufacturing process many of the proteins degrade, denature and lose their activity, however, some proteins retain their allergenic properties throughout the process. Latex products can have high protein but low allergen levels and vice versa.

Why have we chosen Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02 to be included in the kits? 

According to the current literature, these four allergens are the ones that have been unequivocally demonstrated to be present in glove extracts and to resist the glove-manufacturing process.[1] 

Please forward all your technical questions to: technical.support@icosagen.ee