Mouse mAb to MLV p30 (clone 4B2)

Catalogue #

A2-301-100

Name

Mouse mAb to MLV p30 (clone 4B2)

Target

MLV p30

Target Description

Full length recombinant MLV-Gag p30 capside protein, purified from E. coli

Clonality

Mouse monoclonal

Clone

4B2

Class

IgG

Reactivity

MLV Gag, p30

Application

ELISA, WB

Protocol

ELISA:

0,05-0,1 µg/ml

WB:

0,5 µg/ml

Purification

Protein G purification

Buffer

PBS pH 7.4, 0.1% sodium azide

Shipping

This product is shipped in non-frozen liquid form in ambient conditions

Storage

Store at -20…-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles

Background

Murine leukemia viruses belong to family of Retroviruses group and are named for their ability to cause cancer in mice. Some form of MLV’s are used in cancer research. The retroviral Gag protein plays important roles at several stages in the viral life cycle. Late in infection, the Gag precursor protein acts to mediate the assembly and release of virion particles. After budding, the core matures by cleavage of Gag precursor protein into the mature core proteins, the matrix (MA), capsid (CA) and nucleocapsid proteins. These separated Gag proteins then play roles in the early stages of infection