Mouse mAb hARTN (clone 2A5)

Catalogue #

323-100

Name

Mouse mAb hARTN (clone 2A5)

Target

Human Artemin

Target Description

Recombinant human Artemin protein produced using CHO-based Icosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purified from cell culture supernatant

Alternative Names

Enovin, Neublastin

Uniprot ID

Q5T4W7

Clonality

Mouse monoclonal

Clone

2A5

Class

mIgG1

Reactivity

Human Artemin

Application

ELISA, WB, IF

Protocol

ELISA:

0,2-1 µg/ml

WB:

0,5-2 µg/ml (detects only dimeric protein in non-reducing conditions)

IF:

0,3-20 µg/ml

Purification

Protein G purification

Buffer

PBS pH 7.4, with 0.1% sodium azide

Shipping

This product is shipped in non-frozen liquid form in ambient conditions

Storage

Store at –20…-70°C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles

Background

Artemin supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex (UniProt)