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2B4-His, human recombinant

 

Figure 1. SDS-PAGE analysis of human 2B4 visualized by PageBlue protein staining solution (Fermentas). Lane 1. 2 µg of human 2B4 (reduced); Lane 2. Protein size marker ( Prestained protein ladder, 8003, Naxo); Lane 3. 2 µg of human 2B4 (non-reduced).

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Catalogue #

P-404-100

Name

2B4-His, human recombinant

Synonyms

NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, SLAM family member 4, Signaling lymphocytic activation molecule 4, CD_antigen: CD244

Description

Protein contains only extracellular domain of the human 2B4 (aa 22-229)

Uniprot ID

Q9BZW8

Source

Human

MW

Approximately 24.1 kDa, a single non-glycosylated polypeptide chain containing 214 amino acids including C-terminal hexahistidine tag

Host

CHO-based cell line (expressed by QMCF Technology)

Purification

Purified by Ni-affinity chromatography, ion-exchange chromatography and desalting chromatography from serum-free CHO growth media

Concentration

1.1 mg/ml

Buffer

PBS pH 6.0

Endotoxine

Not tested

QC

Coomassie-stained SDS-PAGE

Shipping

Shipped on dry ice

Storage

Store at -70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles

Background

Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family

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This product is for research use only

TECHNICAL ASSISTANCE

Please refer any technical questions to

technical.support@icosagen.com

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