PRINCIPAL SCIENTIST - Antibody therapeutics


Icosagen Cell Factory OÜ Research & Development Department is seeking an experienced PRINCIPAL SCIENTIST - Antibody therapeutics.

Position summary:

The R&D group is seeking a highly motivated experienced Principal Scientist to lead projects in the field of antibody-based therapeutics development – mainly in the field of oncology. The candidate is expected to have 3-5 years of relevant postgraduate academic or industry experience. Background in cell biology, cellular and molecular immunology or protein engineering is expected. The candidate will be responsible for independent design and implementation of hypothesis-based research and team management and leadership. The candidate is expected to support internal and external collaborative
research projects.

Role responsibilities include:

  • Work within a matrix organization to develop antibody and/or cell-based therapeutic approaches against various indications.
  • Provide scientific and team leadership and project management expertise but also
    contribute to the advancement of internal or external collaborative projects. Create and track personal and team objectives.
  • Provide insights into the mechanisms of action of developed immunotherapies and respective disease biology.
  • Design and implement short- and long-term experimental project plans, interpret
    experimental data and define safety, efficacy, mechanisms of action and developability profiles.
  • Establish novel state-of-the-art techniques and assays for functional analysis of
    immunotherapy candidates ex vivo/in vitro.
  • Document all research activities and
    summarize data in progress reports. Internal and external data presentation.
  • Manage and provide team leadership.

Required qualifications:

  • The candidate is expected to have a PhD or similar experience in the field of cell biology, immunology, oncology, translational research, or a related field.
  • The position requires a minimum of 10 years of relevant hands-on wet lab research experience and a strong track record including publications and/or evidence of research output.
  • A thorough skillset in a wide range of state of- the-art molecular and cell biology
    techniques, including primary cell based assays and in-vivo assay design.
  • Basic understanding of cancer biology and treatment, and novel immunotherapies.
  • Proactive, constructive, well-organized and able to think critically and solve problems independently.
  • Be able to communicate research effectively in written and oral English.

We offer:

  • full-time specified-term employment contract for versatile and interesting work in an international company
  • on-site training and a supportive team
  • opportunities for self-realization and development
  • company benefits package and joint events


Work location is in Tartu, Estonia. Employment contract for specified term.

To apply, please submit your letter of motivation along with your resume to          Tel: +372 737 7080

By submitting a letter of motivation and a resume, candidates consent to the processing of their personal data for internal purposes. Documents will be stored for up to one year, allowing to be considered for future opportunities, including similar or alternative positions within the Icosagen group.

Job Location
Tartu, Eesti
Date posted
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