Process Development

QMCF Technology platform and experienced scientists provide customised services to transfer the production process to GMP manufacturing facility.

Protein production

Process Development and technology Transfer

 

Icosagen Cell Factory offers:

  • Optimization of gene, expression vector and medium.  Study on protein expression and stability of plasmid.
  • Best cell line analysis (QMCF/CHO or QMCF/HEK293 cells)
  • Generation of cell banks: RCB, MCB and WCB. The cell banks will be certified from the quality aspects
  • Production process optimization in bioreactor. Analysis of production parameters - pH, oxygen, CO2, feeding regimen, cell growth and productivity levels
  • Purification optimization. Establishment and improvement of purification scheme
  • Protein quality analysis