monoclonal antibody to Hev b5 (Major latex allergen)
fusion protein expressed and purified from E.
Major latex allergen (Hevea brasiliensis)
Recombinant and native Hev b5
ELISA 1:64 000, WB. Reacts as detection antibody in capture
ELISA with Hev b5 binding monoclonal antibody A3-707-100
Protein G affinity purified
PBS, 0.1% sodium azide
A3-707-100 - mouse
monoclonal antibody to Hev b5, used as a binding antibody in pair with detection
antibody A3-708-100 in capture ELISA.
antibodies to Hev b1, Hev b3 and Hev b6.02 are available. For more information
This product is shipped in non-frozen liquid form in
Store at - 20 …-70 °C upon receipt. Divide antibody
into aliquots prior usage. Avoid multiple freeze-thaw cycles as product
degradation may result
Liquid latex from the rubber tree, Hevea brasiliensis,
is the source of natural rubber latex (NRL) and contains over 200 proteins; 14
of them have been identified as allergens. Only some allergens retain their
allergenic properties through the manufacturing processes. The NRL allergens
that have been shown to be clinically relevant to genuine NRL allergy, and
present in the final NRL products with maintained allergenicity are Hev b1, Hev
b3, Hev b5 and Hev b6.02.
ASTM D7427 - 08e1
Standard Test Method for Immunological Measurement of Four Principal Allergenic
Proteins (Hev b 1, 3, 5 and 6.02) in Natural Rubber and Its Products Derived
D, Ng V, Leow YH, Goh CL. (2005) A study of natural rubber latex
allergens in gloves used by healthcare workers in Singapore. Br J Dermatol.
T, Alenius H, Turjanmaa K. (2002) Quantitation of latex allergens.
C, Tavares-Ratado P, Tomás MR, Taborda-Barata L, Tomaz CT. (2008)
Latex allergy: new insights to explain different sensitization profiles in
different risk groups. Br J Dermatol. 159(1):132-6.
Kang PB, Vogt K, Gruninger SE, Marshall M, Siew C,
(2007) The immuno cross-reactivity of gutta percha points. Dent Mater.
product is for research use only